Microsoft OS and SQL Server Compatibility Matrix

Clinical is distributed with the free Microsoft SQL Server 2014 SP3 Express Edition.

  • SQL Server 2014 SP3 Express Edition has a maximum database limit of 10GB. For larger databases, full Microsoft SQL Server is required. If you want to use a full Microsoft SQL Server product, consult the compatibility matrix below.
  • The SQL Server installation cannot be made on read-only, mapped, or compressed drives, and SQL Server setup via Terminal Services Client is not supported.
  • Ensure you have a minimum .NET 3.5 installed in order to run the SQL Server 2014 installation.
  • The SQL Server 2014 installation will install .NET4.0 automatically if not already present. This requires an active internet connection for the .NET4.0 installation files to be downloaded.
  • If you have a Server Core installation of Windows Server 2008 R2 SP1 or Windows Server 2012, you must install .NET 4.0 manually, before you install SQL Server Express.
  • Always install the latest Service Pack.
Table 1. Minimum Supported Microsoft SQL Server Products
OS-SQL Compatibility SQL 2005 SP3 SQL 2008 R2 SQL 2012 SQL 2014 SQL 2016 SQL 2017 SQL 20191 SQL 2022
Server 2003 Service Pack 2 (including SBS) (32-bit) - - - - - - - -
Server 2008 R1 - - - - - - - -
Small Business Server (SBS) 2008 (64-bit)

Clinical requires at least Service Pack 2

- - - - -
Server 2008 R22 - - - - -
Server 20122 - - -
Server 2012 R2 2 - - -
Server 2016 - - -
Server 2019 - - - - - -
Server 2022 - - - - - -
XP Home Service Pack 3, (32-bit)

Standalone or peer-to-peer w/ other XP Home only

- - - - - - - -
XP Pro Service Pack 2, (32-bit) - - - - - - - -
XP Pro Service Pack 3, (32-bit) - - - - - - - -
Windows Vista Business/Ultimate/Enterprise3 Service Pack 1

*Requires Service Pack 2

- - - - - - - -
Windows 74

*Clinical requires at least Service Pack 1

- 5 - - - -
Windows 8

Excludes Windows RT

- - - - - - - -
Windows 8.1

Excludes Windows RT

- 5 6 6 - -
Windows 107 - 8 6 6 -
Windows 11 - - -
1 You will require a minimum 6GB hard drive space to install SQL Server 2019, plus a minimum 5GB space for the MedicalDirector database. SQL requires at least a 1.4 GHz processor, with 2.0GHz recommended.
2 Microsoft provides only a 64-bit version.
3 Home Basic/Premium will install Clinical 4.3 but is not recommended. Should not be used in a Server role for Clinical.
4 Home Premium has limited functionality, recommended only for Standalone Servers, or in a simple network with other Windows 7 Home Premium PCs.
5 SQL Server 2014 Standard only.
6 Operating System does not support SQL Server Enterprise Editions.
7 When you run Clinical for the first time after upgrading to Windows 10, the Clinical installation may repair itself. In the majority of cases, the repair process completes automatically – no user interaction is required. However, if you are prompted for the installer, contact MedicalDirector Customer Service for assistance.
8 Any version. SP1 is required.